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Trudy 时间: 11-01 07:01   主题:无标题
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Libby 时间: 11-01 06:58   主题:无标题
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Murray 时间: 11-01 06:55   主题:无标题
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Michelle 时间: 11-01 06:53   主题:无标题
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Dennis 时间: 11-01 06:48   主题:无标题
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Larhonda 时间: 11-01 06:41   主题:无标题
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Lucas 时间: 11-01 06:35   主题:无标题
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Nick 时间: 11-01 06:34   主题:无标题
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Cecilia 时间: 11-01 06:29   主题:无标题
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The mechanism of toxicity remains poorly understood but it has been advised to end result from AR activation in liver cells resulting in an increased production of reactive oxygen species (ROS) (11).
Due To This Fact AAS with adequate resistance to hepatic breakdown and efficiency to activate the AR are vulnerable to incur liver damage. The scientific relevance of elevated biochemical markers of liver harm in response to AAS use remains unknown.
With Out structural modification to resist first-pass metabolism a big fraction of the absorbed AAS will be metabolized earlier than leaving the liver and re-entering the circulation. For instance after oral administration of 25 mg testosterone lower than 1 mg (4%) becomes systemically out there (9).
The oral bioavailability of AAS could be increased by making the father or mother molecule more lipid-soluble by the esterification process described within the previous paragraph.
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Brodie 时间: 11-01 06:14   主题:无标题
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